Diagnostic Value Of Qtc Dispersion And And Qt Dispersion Ratio Changes On Stress Test In Detecting Significance Of Coroner Lesion In Stable Angina Pectoris Patients

Abstract

Introduction

QT dispersion, an electrocardiographic marker of ventricular repolarization heterogeneity, is increasingly investigated for its value in detecting coronary lesions in stable angina pectoris. This review synthesizes evidence on its diagnostic and prognostic utility in coronary artery disease.

Methods

This abstract is based on a literature review synthesizing findings from multiple clinical studies. The review examined the correlation between QT dispersion and the severity of coronary artery disease, as well as its response to revascularization procedures like percutaneous coronary intervention (PCI).

Results

Increased QT dispersion is prevalent in patients with chronic stable angina, reflecting underlying ischemic processes. Studies show a significant correlation between corrected QT (QTc) dispersion and the severity of coronary artery disease, as measured by the SYNTAX score. Following successful PCI, there is a significant reduction in QTc dispersion, indicating its potential as a marker for successful reperfusion. Furthermore, prolonged QT dispersion is associated with an increased risk of malignant ventricular arrhythmias.

Discussion

QT dispersion serves as a simple, non-invasive, and cost-effective tool for risk stratification and assessing myocardial ischemia. Its ability to reflect both lesion severity and reperfusion success makes it a valuable clinical indicator. However, the lack of standardized measurement techniques and validated clinical thresholds currently limits its widespread application and generalizability.

Conclusion

QT dispersion is a valuable diagnostic and prognostic marker in patients with stable angina and coronary artery disease. The integration of standardized QT dispersion measurements into clinical practice could enhance patient management, but further large-scale research is needed to establish clear guidelines and validate its use across diverse populations.