Focus And Scope

The American Journal of Natural Medicine, published by American Medical Publication collaborates with American Medical Association. are dedicated to providing physicians with the best research and important information in the world of medical research and science and to present the information in a format that is understandable and clinically useful. Committed to publishing multidisciplinary research that spans the entire spectrum of healthcare and medicine access, The American Journal of Natural Medicine aims at an international audience of pharmacists, clinicians, medical ethicists, regulators, and researchers, providing an online forum for the rapid dissemination of recent research and perspectives in this area.

The American Journal of Natural Medicine Evidence seeks to advance clinical trial research and clinical practice by:

• Publishing high-quality studies from the front lines of medical research.
• Challenging the medical community to take new approaches to clinical trial design and execution that yield more powerful clinical evidence.
• Sparking debate and conversation around areas of medicine where clinical decisions are made without sufficient evidence.
• Engaging physicians in a more sophisticated and meaningful way with clinical evidence.

Adhering to the rigorous peer-review and quality standards expected from The American Journal of Natural Medicine Evidence publishes:

• Original research, clinical trials, and other clinically grounded work (e.g., epidemiology studies, first-in-human trials, meta-analyses) that validate or challenge prior clinical findings.
• Standard reviews, systematic reviews, and other review types that contextualize research findings with the aim of accelerating clinical adoption of new evidence.
• Case studies and reviews of clinical trial methodology that enhance understanding of trial strengths and weaknesses.
• Curbside consult series that addresses common patient care issues.
• Morning Report series solicited case presentation articles that are delivered in a morning report format.

Generation of Evidence

The process of generating evidence is a key area of focus for The American Journal of Natural Medicine Evidence. We encourage readers to evaluate the reasoning behind the complex decisions that investigators make in trial design and execution, and to assess the quality of evidence produced in trials. Our goal is to build a community that takes a rigorous approach to evaluating evidence and assessing its impact on clinical decision-making.

Statistical Methods

The American Journal of Natural Medicine Evidence guides readers toward a deeper understanding of the statistical methods used in trials. We provide concise, digestible explanations of research methods to inform the interpretation of the resulting data. In addition, we introduce readers to emerging statistical methods and types of data that will play an increasingly prominent role in future trials.

Multidisciplinary Coverage

The American Journal of Natural Medicine Evidence publishes content relevant across all medical disciplines to advance the discussion of how to generate evidence that informs patient care. Physician-scientists, trialists, and general medicine and subspecialty clinicians will all benefit from this publication.

The American Journal of Natural Medicine covers themes including, but not limited to:

• Pharmacognosy and Phytochemistry

• Isolation, purification, and structural elucidation of bioactive compounds from plants, fungi, microorganisms, marine organisms, and animals.
• Chemistry of medicinal plants and other natural sources.
• chemotaxonomy and chemical fingerprinting of natural products.
• Development of new extraction and isolation techniques.

• Pharmacology and Toxicology of Natural Products

• In vitro and in vivo evaluation of the biological activities of natural products (e.g., anticancer, anti-inflammatory, antimicrobial, antioxidant, immunomodulatory).
• Pharmacodynamic and pharmacokinetic studies of natural compounds and standardized extracts.
• Molecular mechanisms of action of natural medicines.
• Toxicological assessment and safety evaluation of natural products and herbal preparations.
• Drug-herb interaction studies.

• Ethnopharmacology and Traditional Medicine

• Scientific validation of traditional and folk medicines from around the world (e.g., Traditional Chinese Medicine, Ayurveda, Jamu, Kampo, Unani).
• Ethnobotanical and ethnomedical surveys documenting the traditional use of medicinal plants.
• Bio-prospecting for new drugs based on traditional knowledge.

• Analytical Methods and Quality Control

• Development and application of chromatographic (HPLC, GC) and spectroscopic (MS, NMR) techniques for the analysis of natural products.
• Standardization and quality control of herbal medicines, crude drugs, and dietary supplements.
• Development of reference standards for active markers and phytochemicals.
• Metabolomics and proteomics approaches in natural medicine research.

• Biotechnology and Biosynthesis of Natural Products

• Plant cell, tissue, and organ culture for the production of secondary metabolites.
• Biosynthetic pathways of bioactive natural compounds.
• Metabolic engineering and synthetic biology for the enhanced production of natural compounds.
• Fermentation technology for producing bioactive substances from microorganisms.

• Clinical Research on Natural Medicines

• Randomized controlled trials (RCTs) evaluating the efficacy and safety of natural medicines and herbal formulations.
• Observational studies, cohort studies, and case-control studies on the use and effects of natural products.
• Systematic reviews and meta-analyses of clinical trials in natural medicine.
• Pharmacovigilance of herbal medicines.

• Nutraceuticals and Functional Foods

• Scientific investigation of foods and isolated food components for disease prevention and treatment.
• The role of dietary supplements and functional foods in human health.
• Elucidation of the active components and mechanisms of action of nutraceuticals.